Dr. Hong Song is a post-doctoral fellow in the Radionuclide Therapy and Dosimetry Research Lab, Division of Nuclear Medicine in the Russell H. Morgan Department of Radiology and Radiological Science at The Johns Hopkins University, School of Medicine.  He received his Bachelor’s degree in Biochemical Engineering from East China University of Science and Technology in China and his Ph.D. in Chemical and Biomolecular Engineering and M.S. in Molecular and Cellular Biology both from Tulane University in New Orleans.

Dr. Song has worked on in vitro three-dimensional tumor model for drug testing and soft tissue engineering using stromal progenitor cells in human adipose tissue.  Title of his Ph.D. thesis is “Spatial Assembly and Composition of Prostate Cancer Spheroid".

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Research

Dr. Song is currently working on targeted therapy of breat cancer metastases using alpha-particle emmitter (Bi-213, Ac-225) labled monoclonal antibodies and other targeting vehicles.  He is the recipient of the Multidisciplinary Postdoctoral Award from Department of Defense Breast Cancer Research Program (BCRP).  The proposed project is titled “Combination Treatment of HER2/neu Expressing Breast Cancer Metastasis by Targeted alpha-Particle Radioimmunotherapy and Cancer Vaccine”. The overall objective of the project is to test the strategy of treating metastatic breast cancer using cancer vaccines, in combination with targeted alpha-particles to overcome tumor immunosuppression. 

PUBLICATIONS

Three-Dimensional Radiobiological Dosimetry (3D-RD): Application of Radiobiological Modeling to Patient-Specific, 3-D Imaging-based Internal Dosimetry, Andrew R Prideaux, Hong Song, Robert F Hobbs, Bin He, Eric C Frey, Paul W Ladenson, Richard L Wahl, and George Sgouros. In process accepted J. Nuc. Med.

Therapuetic potential of Y-90 and I-131 labled anti-CD-20 monoclonal antibody in treating non hodgkin's lymphoma with pulmonary involvement, Song H, Du Y, Sgouros G, Prideaux A, Frey E, Wahl RL. J. Nucl. Med. 2007 Jan: 48 (1):150-7

Lung dosimetry for radioiodine treatment planning in the case of diffuse lung metastases, Song H, He B, Prideaux A, Du Y, Frey E, Kasecamp W, Ladenson PW, Wahl RL, Sgouros G. J Nucl. Med. 2006 Dec; 47(12):1985-94