There are currently a number of ongoing clinical trials in the Mood Disorders Program to test new medications for treatment of major depression and bipolar disorder.
In order to participate in clinical trials, interested volunteers must meet certain requirements, called inclusion and exclusion criteria. These can include such characteristics as been diagnosed with a particular mood disorder and/or belonging to a certain age range. The criteria are listed with each clinical trial description. If researchers find that potential research participants meet the criteria, they are invited to come to The Johns Hopkins Hospital for one or more screening visits. The visits involve a thorough evaluation to determine whether someone is appropriate for that particular study. Even if someone does not join the clinical trial, they are still compensated for their time spent at the screening visits.
Volunteers who have been diagnosed with bipolar disorder or major depression are currently being recruited for studies. The name of the study refers to the name of the medication being tested. If you are interested, please follow the links below:
BIPOLAR DISORDER CLINICAL TRIALS
- Riluzole
Double-blind Placebo-Controlled Trial of Riluzole in Bipolar Depression - Valacyclovir
Double-Blind Placebo-Controlled Trial of Valacylcovir in Cognitive Impairment and Mood Symptoms of Bipolar Disorder
CONTACT US If you cannot participate now but would like to be notified of future research opportunities, please call to be added to our mailing list. |
STAFF PROFILES
| Jennifer L. Payne, M.D. is the principal investigator on the study and an expert in the treatment of affective disorders. Dr. Payne received her B.S. in Biology at Davidson College in Davidson, NC and her medical degree from Washington University Medical School in St. Louis, MO. During medical school she was the recipient of the prestigious Howard Hughes Medical Institute Fellowship and spent a year at the NIH performing basic laboratory research in Alzheimer’s disease. She completed her residency in psychiatry at the Johns Hopkins Hospital where she served as chief resident during her final year. She completed her fellowship in the Mood and Anxiety Disorders Program at the National Institutes of Health and has returned to Johns Hopkins Hospital to conduct her own research. Dr. Payne’s research interests focus on the underlying pathophysiology of mood disorders and the development of novel therapeutic treatments for depression and bipolar disorder. Dr. Payne is a member of the American Psychiatric Society and has received several awards including the NIMH Outstanding Resident Award, the Laughlin Fellowship through the American College of Psychiatrists, and the APA/Lilly Resident Research Award. More about Dr. Payne. |
| Francis M. Mondimore M.D. was a member of the Hopkins faculty from 1984 to 1987. He returned to Hopkins in 1999 after caring for patients in Charlotte, N.C. and serving on the faculty of the University of North Carolina at Chapel Hill. He has authored several books, including "Depression: The Mood Disease,” “Bipolar Disorder: A Guide for Patients and Families”, “A Natural History of Homosexuality”, and “Adolescent Depression: A Guide for Parents.” More about Dr. Mondimore. |
 | Patricia Roy, M.D. is a post-doctoral clinical fellow, working on the Riluzole study. She completed her bachelor's degree in Psychology at the George Mason University and her medical degree at Drexel University College of Medicine in Philadelphia, where she was elected to the Alpha Omega Alpha Honor Society and received a Janet M. Glasgow Achievement Award from the American Medical Women’s Association. Dr. Roy completed her internship year at Lenox Hill Hospital in New York City and she will be completing her residency at Johns Hopkins Hospital. |
