HOPKINS CHILDREN'S CARDIOLOGIST HUNTS BIOMARKERS OF PULMONARY HYPERTENSION
DID U TK UR MEDS?
ONE STEP CLOSER TO CLOSURE
STEROID INJECTIONS MAY SLOW DIABETES-RELATED EYE DISEASE
UP A LITTLE ON THE LEFT ... NOW, OVER TO THE RIGHT ...
Seven Johns Hopkins Researchers Named AAAS Fellows
|12/14/09||WHO GETS EXPENSIVE CANCER DRUGS? A TALE OF TWO NATIONS |
The well-worn notion that patients in the United States have unfettered access to the most expensive cancer drugs while the United Kingdom’s nationalized health care system regularly denies access to some high-cost treatments needs rethinking, a team of bioethicists and health policy experts says in a report out today.
|12/14/09||DARWIN UPDATED: JOHNS HOPKINS SCIENTISTS SUGGEST CERTAIN GENES BOOST CHANCES FOR DISTRIBUTING A WIDE VARIETY OF RANDOM TRAITS AND DRIVE EVOLUTION|
Genes that don’t themselves directly affect the inherited characteristics of an organism but leave them increasingly open to variation may be a significant driving force of evolution, say two Johns Hopkins scientists.
|12/8/09||GENE THERAPY AND STEM CELLS SAVE LIMB|
Blood vessel blockage, a common condition in old age or diabetes, leads to low blood flow and results in low oxygen, which can kill cells and tissues. Such blockages can require amputation resulting in loss of limbs. Now, using mice as their model, researchers at Johns Hopkins have developed therapies that increase blood flow, improve movement and decrease tissue death and the need for amputation. The findings, published online last week in the early edition of the Proceedings of the National Academy of Sciences, hold promise for developing clinical therapies.
|12/7/09||H1N1 MORE RISKY THAN SEASONAL FLU IN CHILDREN WITH SICKLE CELL DISEASE|
Infection with the H1N1 virus, or swine flu, causes more life-threatening complications than seasonal flu in children with sickle cell disease, according to research from Johns Hopkins Children’s Center. The findings, to be presented on Dec. 7 at the annual meeting of the American Society of Hematology, warn parents and caregivers that such children are more likely to need emergency treatment and stays in an intensive-care unit.
POTENTIAL NEW “TWIST” IN BREAST CANCER DETECTION
STEM CELLS BATTLE FOR SPACE
|12/3/09||ECSTASY USE MAY LEAD TO SLEEP APNEA|
--Illegal “club drug” poisons neurons involved in control of breathing during sleep
Repeated use of the drug popularly known as “ecstasy” significantly raises the risk of developing sleep apnea in otherwise healthy young adults with no other known risk factors for the sleep disturbance, a new study by Johns Hopkins scientists suggests. The finding is the latest highlighting the potential dangers of the amphetamine-style chemical, currently used illegally by millions of people in the United States.
FIRST REPORTED CASES OF TAMIFLU-RESISTANT H1N1 FLU IN MARYLAND TREATED AT AND DISCHARGED FROM THE JOHNS HOPKINS HOSPITAL?
|11/25/09||MEDICAL STUDENTS REGULARLY STUCK BY NEEDLES, OFTEN FAIL TO REPORT INJURIES |
--Johns Hopkins research suggests least-skilled providers at risk for life-threatening infections
Medical students are commonly stuck by needles — putting them at risk of contracting potentially dangerous blood-borne diseases — and many of them fail to report the injuries to hospital authorities, according to a Johns Hopkins study published in the December issue of the journal Academic Medicine.
|11/23/09||JOHNS HOPKINS RESEARCHERS TRACK DOWN PROTEIN RESPONSIBLE FOR CHRONIC RHINOSINUSITIS WITH POLYPS|
--New target may eventually help doctors treat often intractable disease
A protein known to stimulate blood vessel growth has now been found to be responsible for the cell overgrowth in the development of polyps that characterize one of the most severe forms of sinusitis, a study by Johns Hopkins researchers suggests. The finding gives scientists a new target for developing novel therapies to treat this form of the disease, which typically resists all current treatments.
|11/20/09||BURNED OUT, DEPRESSED SURGEONS MORE LIKELY TO COMMIT MORE MAJOR MEDICAL ERRORS|
--Factors putting patients at risk go well beyond fatigue, largest study of its kind suggests
Surgeons who are burned out or depressed are more likely to say they had recently committed a major error on the job, according to the largest study to date on physician burnout. The new findings suggest that the mental well-being of the surgeon is associated with a higher rate of self-reported medical errors, something that may undermine patient safety more than the fatigue that is often blamed for many of the medical mistakes.
|11/20/09||HIGH BLOOD PRESSURE EASY TO MISS IN CHILDREN WITH KIDNEY DISEASE |
Spot blood pressure readings in children with chronic kidney disease often fail to detect hypertension – even during doctor’s office visits — increasing a child’s risk for serious heart problems, according to research from Johns Hopkins Children’s Center and other institutions. A report of the findings appears online in the Journal of American Society of Nephrology.
|11/20/09||KENNETH L. BAUGHMAN, M.D., 63, FORMER JOHNS HOPKINS FACULTY PHYSICIAN, REMEMBERED BY FELLOW CARDIOLOGISTS|
The Johns Hopkins Medicine community mourns the sudden death of cardiologist Kenneth L. Baughman, M.D., who was killed in an accident Monday while running in Orlando, Fla. He was attending the annual Scientific Sessions of the American Heart Association, and had attempted to cross a street when a car struck him.
|11/19/09||SWEET! SUGARED POLYMER A NEW WEAPON AGAINST ALLERGIES AND ASTHMA|
Scientists at Johns Hopkins and their colleagues have developed sugar-coated polymer strands that selectively kill off cells involved in triggering aggressive allergy and asthma attacks. Their advance is a significant step toward crafting pharmaceuticals to fight these often life-endangering conditions in a new way.
|11/19/09||MOTHER’S DEPRESSION A RISK FACTOR IN CHILDHOOD ASTHMA SYMPTOMS, STUDY SUGGESTS|
-Results may be tied to fatigue and forgetfulness in managing children’s disease
Asthma symptoms can worsen in children with depressed mothers, according to research from Johns Hopkins Children’s Center published online in the Journal of Pediatric Psychology.
|11/18/09||VITAMIN B NIACIN OFFERS NO ADDITIONAL BENEFIT TO STATIN THERAPY IN SENIORS ALREADY DIAGNOSED WITH CORONARY ARTERY DISEASE |
--Blood cholesterol levels improved, but arteries do not show it
The routine prescription of extended-release niacin, a B vitamin (1,500 milligrams daily), in combination with traditional cholesterol-lowering therapy offers no extra benefit in correcting arterial narrowing and diminishing plaque buildup in seniors who already have coronary artery disease, a new vascular imaging study from Johns Hopkins experts shows.
|11/17/09||NEED FOR EMERGENCY AIRWAY SURGERY FOR HARD-TO-INTUBATE PATIENTS REDUCED|
--Johns Hopkins program offers model as more patients appear with hard to navigate airways
Be prepared, that old Boy Scout motto, is being applied with great success to operating room patients whose anatomy may make it difficult for physicians to help them breathe during surgery, Johns Hopkins researchers report in a new study.
|11/16/09||RAPID, ERRATIC HEARTBEATS: EXERCISE-LINKED VENTRICULAR TACHYCARDIA IS NOT A RISK TO HEALTHY OLDER ADULTS|
Healthy, older adults free of heart disease need not fear that bouts of rapid, irregular heartbeats brought on by vigorous exercise might increase short- or long-term risk of dying or having a heart attack, according to a report by heart experts at Johns Hopkins and the U.S. National Institute on Aging (NIA).
|11/16/09||MIGRAINE RAISES RISK OF MOST COMMON FORM OF STROKE |
--Women more at risk than men; risk particularly high in those with visual symptoms Pooling results from 21 studies, involving 622,381 men and women, researchers at Johns Hopkins have affirmed that migraine headaches are associated with more than twofold higher chances of the most common kind of stroke: those occurring when blood supply to the brain is suddenly cut off by the buildup of plaque or a blood clot.
HEART EXPERTS SAY EARLY END TO KEY STUDY ON BENEFITS OF NIACIN, A B VITAMIN, IN KEEPING ARTERIES OPEN WAS PREMATURE
|11/15/09||‘SCAFFOLDING’ PROTEIN CHANGES IN HEART STRENGTHEN LINK BETWEEN ALZHEIMER’S DISEASE AND CHRONIC HEART FAILURE|
A team of U.S., Canadian and Italian scientists led by researchers at Johns Hopkins report evidence from studies in animals and humans supporting a link between Alzheimer’s disease and chronic heart failure, two of the 10 leading causes of death in the United States.
|11/15/09||HEART AND BONE DAMAGE FROM LOW VITAMIN D TIED TO DECLINES IN SEX HORMONES |
-- Effects of vitamin D deficiency amplified by shortage of estrogen
Researchers at Johns Hopkins are reporting what is believed to be the first conclusive evidence in men that the long-term ill effects of vitamin D deficiency are amplified by lower levels of the key sex hormone estrogen, but not testosterone
YOUNG ATHLETES NEED DUAL SCREENING TESTS FOR HEART DEFECTS, STUDY SUGGESTS
|11/9/09||BACK PAIN PERMANENTLY SIDELINES SOLDIERS AT WAR|
--Few rejoin units in Iraq or Afghanistan, regardless of treatment
Military personnel evacuated out of Iraq and Afghanistan because of back pain are unlikely to return to the line of duty regardless of the treatment they receive, according to research led by a Johns Hopkins pain management specialist.
|11/6/09||1930s DRUG SLOWS TUMOR GROWTH|
Drugs sometimes have beneficial side effects. A glaucoma treatment causes luscious eyelashes. A blood pressure drug also aids those with a rare genetic disease. The newest surprise discovered by researchers at the Johns Hopkins University School of Medicine is a gonorrhea medication that might help battle cancer.
|11/4/09||SCIENTISTS REVEAL HOW INDUCED PLURIPOTENT STEM CELLS DIFFER FROM EMBRYONIC STEM CELLS AND TISSUE OF DERIVATION|
Scientists Reveal How Induced Pluripotent Stem Cells Differ From Embryonic Stem Cells and Tissue of Derivation
The same genes that are chemically altered during normal cell differentiation, as well as when normal cells become cancer cells, are also changed in stem cells that scientists derive from adult cells, according to new research from Johns Hopkins and Harvard.
|11/4/09||TEEN GIRLS DIAGNOSED WITH STI MORE LIKELY TO TELL?AND SEEK TREATMENT FOR PARTNERS AFTER WATCHING|
Teen Girls With PID More Likely To Tell and Seek Treatment For Partners After Watching Video
A study at Johns Hopkins Children’s Center found that girls diagnosed with pelvic inflammatory disease (PID) who watched a short educational video were three times more likely to discuss their condition with their partners and to ensure partner treatment than girls diagnosed and treated without seeing the film.
LOW CHOLESTEROL MAY SHRINK RISK FOR HIGH-GRADE PROSTATE CANCER
THIS IS YOUR BRAIN ON FATTY ACIDS
SIGHT GONE, BUT NOT NECESSARILY LOST?
OF MICE AND MEN: STEM CELLS AND ETHICAL UNCERTAINTIES
'MOONLIGHTING' MOLECULES DISCOVERED
LESSONS FROM FLU SEASONS PAST: RISK OF SERIOUS FLU-RELATED SICKNESS FAR OUTPACES RISK OF INJECTABLE VACCINE IN PREGNANT WOMEN
LACK OF INSURANCE MAY HAVE FIGURED IN NEARLY 17,000 CHILDHOOD DEATHS, STUDY SHOWS
|10/27/09||MUSCLE WEAKNESS A COMMON SIDE EFFECT OF LONG STAYS IN INTENSIVE CARE UNITS |
--Doctors need better definitions to prevent and treat physical debility among critically ill
After decades of focusing on the management of respiratory failure, circulatory shock and severe infections that lead to extended stays in hospital intensive care units, critical care researchers are increasingly turning attention to what they believe is a treatable complication developed by many who spend days or weeks confined to an ICU bed: debilitating muscle weakness that can linger long after hospital discharge.
|10/26/09||NEW "SCHIZOPHRENIA GENE" PROMPTS RESEARCHERS TO TEST POTENTIAL DRUG TARGET|
Johns Hopkins scientists report having used a commercially available drug to successfully “rescue” animal brain cells that they had intentionally damaged by manipulating a newly discovered gene that links susceptibility genes for schizophrenia and autism.
|10/23/09||NOW HEAR THIS|
-- Johns Hopkins Scientists Show How Tiny Cells Deliver Big Sound?
Deep in the ear, 95 percent of the cells that shuttle sound to the brain are big, boisterous neurons that, to date, have explained most of what scientists know about how hearing works. Whether a rare, whisper-small second set of cells also carry signals from the inner ear to the brain and have a real role in processing sound has been a matter of debate.
|10/22/09||PHYSICIANS HAVE LESS RESPECT FOR OBESE PATIENTS, STUDY SUGGESTS|
--Findings raise questions about whether docs’ negative attitudes affect patients’ health
Doctors have less respect for their obese patients than they do for patients of normal weight, a new study by Johns Hopkins researchers suggests. The findings raise questions about whether negative physician attitudes about obesity could be affecting the long-term health of their heavier patients.
|10/21/09||$3.7 MILLION NIH GRANT WILL FUND STUDY ON STEM CELLS DERIVED FROM ALS PATIENTS|
Johns Hopkins scientists have been awarded a $3.7 million grant from the National Institutes of Health (NIH) to learn more about the nerve and muscle-wasting disease amyotrophic lateral sclerosis (ALS) using stem cells developed from ALS patients’ skin. The award, given over a two-year span, will be shared with three other laboratories, including one at Harvard University and two at Columbia University.
|10/20/09||NEW ANNE AND MIKE ARMSTRONG MEDICAL EDUCATION BUILDING DEDICATED|
State-of-the-art building will be home of revolutionary new medical education curriculum
More than a century ago, Johns Hopkins revolutionized the teaching of medicine with a new curriculum that merged evidence-based science with patient-centered clinical care. This so-called Hopkins model became the national gold standard for modern medical education.
|10/19/09||JOHNS HOPKINS RESEARCHERS AT SOCIETY FOR NEUROSCIENCE ANNUAL MEETING|
--Chicago, Il, October 17-21
HISPANIC CHILDREN RARELY GET TOP-NOTCH CARE FOR BRAIN TUMORS
|10/14/09||STEPHANIE DESMON JOINS JOHNS HOPKINS MEDICINE’S MEDIA TEAM|
Stephanie Desmon, an award-winning medical journalist, has joined Johns Hopkins Medicine as a senior media relations representative and public information officer.
PEDIATRIC OTOLARYNGOLOGIST RECEIVES PRESTIGIOUS AWARD
|10/14/09||NEW MEDICAL INFORMATICS JOURNAL TO LAUNCH IN DECEMBER|
Two Johns Hopkins Children’s Center researchers have assembled a 25-member editorial board of international experts to launch a quarterly online medical journal devoted to original research and commentary on the use of computer automation in the day-to-day practice of medicine.
|10/12/09||JOHNS HOPKINS RESEARCHERS RECEIVE $1M ARRA AWARD TO “MAP MOBILE DNA IN HUMANS”|
Sequencing the human genome was just one step in understanding our biology: Researchers still know very little about the function of most of our DNA. Now, a team of researchers at the Johns Hopkins University School of Medicine has been awarded $1 million in stimulus funding to examine how certain mobile segments of DNA known as transposons contribute to human genetic diversity by mapping transposon locations in more than 100 people over the next two years.
|10/12/09||“CONSUMER CHOICE” AWARD GOES TO THE JOHNS HOPKINS HOSPITAL FOR THE 14TH CONSECUTIVE YEAR|
For the 14th straight year, the National Research Corporation (NRC) has given The Johns Hopkins Hospital its Consumer Choice Award for the Baltimore region. For 2009-2010, Hopkins also was rated as the top choice by consumers in the Bethesda, Md., area. The award is based on ratings from health care consumers, who assessed hospital standings based on four metrics: best overall quality, best image/reputation; best doctors, and best nurses.
UNEQUAL ACCESS: HISPANIC CHILDREN RARELY GET TOP-NOTCH CARE FOR BRAIN TUMORS
AUTISM: GENOME-WIDE HUNT REVEALS NEW GENETIC LINKS
H1N1 BRIEFING BY LOCAL EXPERTS ON WHAT PARENTS NEED TO KNOW: TAKE PRECAUTIONS, DON’T PANIC AND DON’T OVERREACT
DISCUSSING THE BAD NEWS: WHAT PARENTS OF FETUSES WITH CONGENITAL DEFECTS WANT FROM THEIR DOCTORS
|10/5/09||“TELOMERE” EXPERT CAROL GREIDER SHARES 2009 NOBEL?PRIZE IN PHYSIOLOGY OR MEDICINE |
Carol Greider, Ph.D., 48, one of the world’s pioneering researchers on the structure of chromosome ends known as telomeres, today was awarded the 2009 Nobel Prize in Physiology or Medicine by the Royal Swedish Academy of Sciences. The Academy recognized her for her 1984 discovery of telomerase (ta-LAW-mer-ace), an enzyme that maintains the length and integrity of chromosome ends and is critical for the health and survival of all living cells and organisms.
|10/1/09||“MASK DEBATE” DIVERTING NEEDED ATTENTION FROM FLU-PREVENTIVE MEASURES THAT WORK|
Infection control experts at Johns Hopkins and the U.S. Centers for Disease Control report that a contentious debate in the medical community over what type of protective masks health workers should wear to prevent the spread of H1N1 and other flu viruses is dangerously distracting the health care community from focusing on simple prevention measures that are clearly known to work.
|9/30/09||JOHNS HOPKINS AND USC WIN $10.4 MILLION TO STUDY CANCER EPIGENOME|
The National Cancer Institute (NCI) has awarded $10.4 million to Johns Hopkins and The University of Southern Califonia (USC) to decipher epigenetic marks in the cancer genome. The joint five-year grant is expected to help scientists develop drugs and tests that target epigenetic changes in cancer cells.
|9/30/09||PREVENTING MEDICAL ERRORS: AVOID BLAME GAME, BUT PUNISH HABITUAL OFFENDERS|
Patient safety experts at Johns Hopkins and elsewhere are taking their prescription for avoiding medical errors in hospital care one step beyond already successful “no fault, no blame” approaches, calling now for penalties for doctors and nurses who fail to comply with proven safety measures.
|9/30/09||H1N1 (SWINE INFLUENZA) EXPERTS AT THE JOHNS HOPKINS MEDICAL INSTITUTIONS|
Johns Hopkins has a wide range of experts available for interviews and comments about H1N1 and seasonal flu, emergency preparedness, infection control, transmission in children, vaccine safety, flu treatment, public health ethics, flu in cancer patients, and public communications strategies.?
JOHNS HOPKINS EPIGENETIC CENTER RECEIVES $16.8 MILLION NIH GRANT
|9/24/09||NIH “PIONEER” AND “INNOVATOR” AWARDS GO TO JOHNS HOPKINS SCIENTISTS|
?A Johns Hopkins scientist who proposes to manipulate forces to activate enzymes in live cells, and a second researcher who has developed a way to hunt down tuberculosis germs with real-time imaging have received a total of $4 million in special awards from the National Institutes of Health.
HEALING BADLY DAMAGED LUNGS: DISTINCT SET OF WHITE BLOOD CELLS FOUND TO SET THE PACE OF WOUND REPAIR
MILD EXERCISE WHILE IN THE ICU REDUCES BAD EFFECTS OF PROLONGED BED REST??
|9/21/09||JOHNS HOPKINS LAUNCHES STEM CELL WEB DOCUMENTARY? |
-Multimedia production dovetails with 2009 World Stem Cell Summit in Baltimore, Md.
Johns Hopkins Medicine, a co-host of the 2009 World Stem Cell Summit, is telling a comprehensive stem cell story via a new interactive Web site http://www.hopkinsmedicine.org/stem_cell_research/ on which its researchers and clinicians collectively describe their explorations into stem cell biology and engineering.
|9/21/09||HISTORIC JOHNS HOPKINS MULTIPLE KIDNEY SWAP OPERATIONS TO BE FEATURED ON THE DR. OZ SHOW|
Robert A. Montgomery, M.D., Ph.D., director of the Johns Hopkins Comprehensive Transplant Center and 11 Johns Hopkins patients, who were part of the first eight-way, multihospital, domino kidney transplant this summer, will be featured on the new Dr. Oz Show.
|9/18/09||CHEAP, QUICK BEDSIDE “EYE MOVEMENT” EXAM OUTPERFORMS MRI FOR DIAGNOSING STROKE IN PATIENTS WITH DIZZINESS|
-- Small study demonstrates possibilities of reducing unnecessary MRI tests and improving safety
In a small “proof of principle” study, stroke researchers at Johns Hopkins and the University of Illinois have found that a simple, one-minute eye movement exam performed at the bedside worked better than an MRI to distinguish new strokes from other less serious disorders in patients complaining of dizziness, nausea and spinning sensations.
ANTIOXIDANT CONTROLS SPINAL CORD DEVELOPMENT
|9/16/09||GENETIC HINT FOR RIDDING THE BODY OF HEPATITIS C|
More than seventy percent of people who contract Hepatitis C will live with the virus that causes it for the rest of their lives and some will develop serious liver disease including cancer. However, 30 to 40 percent of those infected somehow defeat the infection and get rid of the virus with no treatment. In this week’s Advanced Online Publication at?Nature, Johns Hopkins researchers working as part of an international team report the discovery of the strongest genetic alteration associated with the ability to get rid of the infection.
|9/16/09||GUIDE ON LUNG CANCER IN “NEVER-SMOKERS”: A DIFFERENT DISEASE AND DIFFERENT TREATMENTS|
---Sixth largest cancer killer
A committee of scientists led by Johns Hopkins investigators has published a new guide to the biology, diagnosis and treatment of lung cancer in never-smokers, fortifying measures for what physicians have long known is a very different disease than in smokers.
|9/15.09||BEST DRESSED SALE SET FOR OCTOBER 1-4|
Some Baltimore traditions just keep getting bigger and better. That's certainly the case with this year's Johns Hopkins Best Dressed Sale and Boutique 2009, now in its 42nd year. Exclusive designer dresses and shoes, chic contemporary fashions, classic accessories and enduring vintage clothing will be on the racks, waiting for a favored place in the closets of bargain-conscious – but demanding – shoppers.
DIVIDING CELLS “FEEL” THEIR WAY OUT OF WARP?
|9/3/09||SURGICAL SCRUB SOLUTION: IT’S GOOD FOR PATIENTS, TOO|
- Chlorhexidine bathing is cheap and effective means of protecting patients from superbugs?
Giving critically ill hospital patients a daily bath with a mild, soapy solution of the same antibacterial agent used by surgeons to “scrub in” before an operation can dramatically cut down, by as much as 73 percent, the number of patients who develop potentially deadly bloodstream infections, according to a new study by patient safety experts at The Johns Hopkins Hospital and five other institutions.
|9/3/09||ANTICANCER DRUG YIELDS POSITIVE RESPONSE IN PEOPLE WITH ADVANCED OR RECURRING SKIN AND BRAIN CANCER|
The Hedgehog signaling pathway is involved in a preliminary study and case report describing positive responses to an experimental anticancer drug in a majority of people with advanced or metastatic basal cell skin cancers. One patient with the most common type of pediatric brain cancer, medulloblastoma, also showed tumor shrinkage.
|8/28/09||HIV SUBTYPE LINKED TO INCREASED LIKELIHOOD FOR DEMENTIA|
--Subtype D may cause one of leading types of dementia worldwide
Patients infected with a particular subtype of HIV, the virus that causes AIDS, are more likely to develop dementia than patients with other subtypes, a study led by Johns Hopkins researchers shows.
|8/26/09||DISCLOSING FINANCIAL CONFLICTS OF INTEREST TO RESEARCH PARTICIPANTS MAY NOT BE ENOUGH|
Disclosure of financial conflicts of interests to potential participants in research is important, but may have a limited role in managing these conflicts, according to a new study by Johns Hopkins, Duke and Wake Forest.
|8/26/09||BRAIN CANCER EXPERTS AT JOHNS HOPKINS|
Johns Hopkins’ Brain Tumor Center is one of the largest brain tumor treatment and research centers in the world. With specialists ranging from neurosurgeons, oncologists, and laboratory researchers currently developing new cutting edge treatments, Johns Hopkins can provide you with unique sources who can answer your timely questions about brain tumors.
|8/25/09||SETTING PRIORITIES FOR PATIENT-SAFETY EFFORTS WILL MEAN HARD CHOICES|
--Johns Hopkins bioethicists and safety experts suggest guidelines for policy makers.
Is it more urgent for hospitals, doctors and nurses to focus resources on preventing the thousands of falls that injure hospitalized patients each year, or to home in on preventing rare but dramatic instances of wrong-side surgery? Is it best to concentrate immediately on preventing pediatric medical errors or on preventing drug interactions in the elderly?
|8/18/09||MILK SAFE, EVEN ENCOURAGED, FOR SOME AFTER TREATMENT FOR MILK ALLERGY |
-Small study followed 18 children for up to 17 months
Some children with a history of severe milk allergy can safely drink milk and consume other dairy products every day, according to research led by the Johns Hopkins Children’s Center and published in the Aug. 10 online edition of the Journal of Allergy and Clinical Immunology.
|8/17/09||COMMON SLEEPING DISORDER UPS CHANCES OF DYING? |
- Study is the first to quantify death rates for sleep apnea, especially in people who snore?
Nightly bouts of interrupted, oxygen-deprived sleep from a collapsed airway in the upper neck raises the chances of dying in middle-aged to elderly people by as much as 46 percent in the most severe cases, according to a landmark study on sleep apnea by lung experts at Johns Hopkins and six other U.S. medical centers.
|8/6/09||JOHN D. STRANDBERG, D.V.M., PH.D., D.A.C.V.P., 1939-2009|
John D. Strandberg, Distinguished Member of the American College of Veterinary Pathologists and former director of the Division of Comparative Medicine at the Johns Hopkins University School of Medicine, passed away on Aug. 1 in St. Paul, Minn. after a long illness. He was 69.
|8/6/09||JOHNS HOPKINS RESEARCHERS MAKE STEM CELLS FROM DEVELOPING SPERM|
The promise of stem cell therapy may lie in uncovering how adult cells revert back into a primordial, stem cell state , whose fate is yet to be determined. Now, cell scientists at the Johns Hopkins University School of Medicine have identified key molecular players responsible for this reversion in fruit fly sperm cells. Reporting online this week in Cell Stem Cell, researchers show that two proteins are responsible redirecting cells on the way to becoming sperm back to stem cells.
COLON CANCER MAY YIELD TO CELLULAR SUGAR STARVATION
|8/06/09||HOPKINS SCIENTISTS FIND CELLS RESPONSIBLE FOR BLADDER CANCER'S SPREAD|
Powerful cells located in same tissue location as bladder stem cells
Johns Hopkins scientists have tracked down a powerful set of cells in bladder tumors that seem to be primarily responsible for the cancer’s growth and spread using a technique that takes advantage of similarities between tumor and organ growth. The findings, reported in the July Stem Cells, could help scientists develop new ways of finding and attacking similar cells in other types of cancer.
|8/03/09||IS THERE LONG-TERM BRAIN DAMAGE AFTER BYPASS SURGERY? MORE EVIDENCE PUTS THE BLAME ON HEART DISEASE ITSELF|
Brain scientists and cardiac surgeons at Johns Hopkins have evidence from 227 heart bypass surgery patients that long-term memory losses and cognitive problems they experience are due to the underlying coronary artery disease itself and not ill after-effects from having used a heart-lung machine.
|7/31/09||MEDIA SOURCE: BIOETHICIST RUTH FADEN CAN DISCUSS THE ETHICAL RAMIFICATIONS OF H1N1 VACCINE PRIORITY GROUP|
Dr. Ruth Faden, director of the Johns Hopkins Berman Institute of Bioethics, is available to discuss the ethical ramifications of this recommendation and other morally challenging dimensions of pandemic influenza, health care reform, and research involving pregnant women.
|7/30/09||HOPKINS PSYCHIATRISTS NAMED “TOP THERAPISTS” BY WASHINGTONIAN MAGAZINE|
Four Johns Hopkins psychiatrists have been named “Top Therapists” in this month’s Washingtonian magazine. The list includes geriatric psychiatrist Peter V. Rabins, M.D., M.P.H.; eating disorders psychiatrist Angela S. Guarda, M.D.; general psychiatrist Todd S. Cox, M.D.; and child and adolescent psychiatrist Elizabeth A. Kastelic, M.D.
|7/30/09||BRING ON THE “SUDS”: PROTOTYPE, 7-FOOT-TALL SANITIZER AUTOMATES DISINFECTION OF HARD-TO-CLEAN HOSPITAL EQUIPMENT|
- SUDS machine designed to reduce infections and cut back on expensive “disposables”
Hopkins experts in applied physics, computer engineering, infectious diseases, emergency medicine, microbiology, pathology and surgery have unveiled a 7-foot-tall, $10,000 shower-cubicle-shaped device that automatically sanitizes in 30 minutes all sorts of hard-to-clean equipment in the highly trafficked hospital emergency department. The novel device can sanitize and disinfect equipment of all shapes and sizes, from intravenous line poles and blood pressure cuffs, to pulse oximeter wires and electrocardiogram (EKG) wires, to computer keyboards and cellphones.
|7/26/09||AN ‘EYE CATCHING’ VISION DISCOVERY|
Nearly all species have some ability to detect light. At least three types of cells in the retina allow us to see images or distinguish between night and day. Now, researchers at the Johns Hopkins School of Medicine have discovered in fish yet another type of cell that can sense light and contribute to vision.
|7/22/09||CLOSE CAREGIVER RELATIONSHIP MAY SLOW ALZHEIMER’S DECLINE|
--Study believed first to document potential impact of emotional closeness on course of disease
A study led by Johns Hopkins and Utah State University researchers suggests that a particularly close relationship with caregivers may give people with Alzheimer’s disease a marked edge over those without one in retaining mind and brain function over time. The beneficial effect of emotional intimacy that the researchers saw among participants was on par with some drugs used to treat the disease.
HEPATITIS C INFECTION: TREATMENT OPTIONS EQUALLY EFFECTIVE, LIKELIHOOD OF SUCCESS KNOWN EARLY ON
|7/20/09||JOHNS HOPKINS CO-SPONSORS 2009 WORLD STEM CELL SUMMIT?|
Johns Hopkins Medicine is co-sponsoring the 2009 World Stem Cell Summit to be held in Baltimore this September.
|7/20/09||DAILY POTASSIUMM CITRATE WARDS OFF KIDNEY STONES IN SEIZURE PATIENTS ON HIGH-FAT DIET?|
Children on the high-fat ketogenic diet to control epileptic seizures can prevent the excruciatingly painful kidney stones that the diet can sometimes cause if they take a daily supplement of potassium citrate the day they start the diet, according to research from Johns Hopkins Children’s Center.
|7/20/09||HOPKINS-DESIGNED ANIMAL TB "TRACKER" TO SPEED DRUG AND VACCINE STUDIES?|
Johns Hopkins researchers have developed a novel way to monitor in real time the behavior of the TB bacterium in mouse lungs noninvasively pinpointing the exact location of Mycobacterium tuberculosis. The new monitoring system is expected to speed up what is currently a slow and cumbersome process to test the safety and efficacy of various TB drug regimens and vaccines in animals. Plans are already under way for developing a similar system to monitor TB disease in humans.
|7/17/09||JOHNS HOPKINS FACULTY MEMBERS AWARDED 2009 WHITE HOUSE EARLY CAREER AWARDS |
Pablo A. Celnik, M.D., an assistant professor of physical medicine and rehabilitation and neurology at the Johns Hopkins University School of Medicine, and Thao (Vicky) Nguyen, 32, assistant professor of mechanical engineering in the Whiting School of Engineering at The Johns Hopkins University, are among the 100 winners of this year’s Presidential Early Career Award for Scientists and Engineers (PECASE).
|7/16/09||JOHNS HOPKINS SCHOOL OF MEDICINE TO OFFER NEW DEGREE PROGRAM IN INFORMATICS|
- ‘Applied Health Sciences Informatics’ Approved by MHEC
A new, intensive, one-year master’s degree program designed to prepare graduates for informatics leadership positions in clinical, public health and scientific settings will be offered beginning in September by the Johns Hopkins University School of Medicine. The Maryland Higher Education Commission (MHEC) approved the new program in June.
|7/16/09||THE JOHNS HOPKINS HOSPITAL TOPS U.S. NEWS & WORLD REPORT “HONOR ROLL” 19TH YEAR IN A ROW|
The Johns Hopkins Hospital has once again – for the 19th consecutive time -- earned the top spot in U.S. News & World Report’s annual rankings of more than 4,800 American hospitals, placing first in three medical specialties and in the top 16 in 13 others.
|7/16/09||JOHNS HOPKINS PHYSICIANS TO PRESENT A CONTINUING MEDICAL EDUCATION COURSE AT AT ST. MATTHEW'S UNIVERSITY SCHOOL OF MEDICINE|
Johns Hopkins Medicine International (JHI) and St. Matthew’s University (SMU), Grand Cayman, Cayman Islands, will present a wide-ranging series of continuing medical education (CME) lectures focusing on new advances in treatment of arthritis and brain tumors, and other topics for local health care professionals and medical students on July 17, 2009.
|7/15/09||RESEARCHERS ID BRAIN-PROTECTING PROTEIN|
Johns Hopkins researchers have discovered a novel protein that can protect brain cells by interrupting a naturally occurring “stress cascade” resulting in cell death.
HOPKINS SURGEON EARNS AWARD FOR LIFETIME ACHIEVEMENT IN PANCREATIC CANCER TREATMENT
|7/9/09||HOPKINS SCIENTIST IS 2009’S OUTSTANDING WOMAN?VETERINARIAN|
A Johns Hopkins veterinarian whose vocation is HIV research and avocation is the care of dog “athletes” has been named the 2009 Outstanding Woman Veterinarian of the Year by the Association for Women Veterinarians Foundation.
ETHICISTS URGE INCLUSION OF PREGNANT WOMEN IN FEDERAL CHILD-HEALTH STUDY
JOHNS HOPKINS LEADS FIRST 16-PATIENT, MULTICENTER “DOMINO DONOR” KIDNEY TRANSPLANT
|7/7/09||WRONG DOSE OF HEART MEDS TOO FREQUENT IN CHILDREN|
-Infants experience errors most often
Infants and young children treated with heart drugs get the wrong dose or end up on the wrong end of medication errors more often than older children, according to research led by the Johns Hopkins Children’s Center to be published July 6 in Pediatrics.
|7/2/09||BIOETHICISTS LEAD CALL FOR PUBLIC DEBATES ON FUTURE USES OF STEM CELLS |
--Science is running ahead of public debate and guidelines to grapple with use of stem cell-derived eggs and sperm.
More than 40 scientists, bioethicists, lawyers and science journal editors are calling on their colleagues, policy makers and the public to begin developing guidelines for the research and reproductive use of stem cell-derived eggs and sperm, even though such use may be a decade or more away.
|7/2/09||SUBURBAN HOSPITAL HEALTHCARE SYSTEM JOINS JOHNS HOPKINS MEDICINE|
-Celebratory Event To Be Held at Suburban July 1, at 3:00 P.M. Ahead of schedule, officials of Suburban Hospital Healthcare System (SHHS) and The Johns Hopkins Health System Corporation completed and signed documents on June 30, 2009, officially integrating the Montgomery County-based SHHS into the Johns Hopkins Health System (JHHS). Under terms of the transaction, which does not involve any financial exchange, SHHS becomes a wholly owned subsidiary corporation of JHHS and a member of Johns Hopkins Medicine (JHM), while retaining its commitment to the local community and community physicians. The SHHS name is not expected to change at this time, and both leadership and day-to-day operations at Suburban will remain the same.
|7/1/09||PREDICTING THE RETURN OF PROSTATE CANCER: NEW JOHNS HOPKINS STUDY BETTERS THE ODDS OF SUCCESS|
Cancer experts at Johns Hopkins say a study tracking 774 prostate cancer patients for a median of eight years has shown that a three-way combination of measurements has the best chance yet of predicting disease metastasis.
|6/29/09||FIGHTING TUBERCULOSIS WITH ANTI-INFLAMMATORY DRUGS SHOWN POSSIBLE IN ANIMAL STUDIES|
Tuberculosis (TB) experts at Johns Hopkins have evidence from a four-year series of experiments in mice that anti-inflammatory drugs could eventually prove effective in treating the highly contagious lung disease, adding to current antibiotic therapies.
VENOM SHOTS WORK FOR SEVERE “LOCAL” STING REACTIONS, TOO
|6/29/09||CRUNCHING THE (SOMETIMES SURPRISING) NUMBERS ON HORMONE-RELATED DISEASE|
A dogged review of the medical literature has produced what is believed to be the nation’s first comprehensive estimate of the extent of dozens of endocrine disorders in the United States.
|6/18/09||JOHNS HOPKINS RESEARCHERS EDIT GENES IN HUMAN STEM CELLS|
Johns Hopkins Researchers Edit Genes in Human Stem Cells
Researchers at the Johns Hopkins School of Medicine have successfully edited the genome of human- induced pluripotent stem cells, making possible the future development of patient-specific stem cell therapies. Reporting this week in Cell Stem Cell, the team altered a gene responsible for causing the rare blood disease paroxysmal nocturnal hemoglobinuria, or PNH, establishing for the first time a useful system to learn more about the disease
|6/18/09||JOHNS HOPKINS SCIENTISTS OUT A GENE FOR GOUT |
Having partnered last year with an international team that surveyed the genomes of 12,000 individuals to find a genetic cause for gout, Johns Hopkins scientists now have shown that the malfunctioning gene they helped uncover can lead to high concentrations of blood urate that forms crystals in joint tissue, causing inflammation and pain — the hallmark of this disease.
HOPKINS CHILDREN'S ON USN&WR LIST OF BEST CHILDREN'S HOSPITALS
|6/17/09||HIV ANTIBODY TESTS UNRELIABLE FOR EARLY INFECTIONS IN TEENS|
A previously healthy teenager shows up at the doctor’s office with a sore throat, fever, aches and general malaise. Routine blood tests are normal, an HIV test comes back negative, and the pediatrician sends the patient home with a diagnosis of acute viral infection.
|6/17/09||ROUX-EN-Y WEIGHT LOSS SURGERY RAISES KIDNEY STONE? RISK|
The most popular type of gastric bypass surgery appears to nearly?double the chance that a patient will develop kidney stones, despite earlier assumptions that it would not, Johns Hopkins doctors report in a new study. The overall risk, however, remains fairly small at about 8 percent.
|6/11/09||LOST MOLECULE IS LETHAL FOR LIVER CANCER CELLS IN MICE? |
-MicroRNA kills tumor cells, lets healthy cells live
Scientists at Johns Hopkins have discovered a potential strategy for cancer therapy by focusing on what’s missing in tumors.
|6/10/09||JOHNS HOPKINS NEUROSCIENTISTS WATCH MEMORIES FORM IN REAL TIME|
Our ability to form long-term memories depends on cells in the brain making strong connections with each other. Yet while it’s not well understood how those connections are made, lost or changed, the process is known to involve the movement of the AMPA receptor protein to and from those neuronal connections
|6/8/09||JOHNS HOPKINS HOLDS RIBBON-CUTTING CEREMONY FOR NEW WILMER EYE INSTITUTE BUILDING|
The Wilmer Eye Institute at Johns Hopkins will celebrate the end of construction of the new Wilmer building at The Johns Hopkins Hospital with a one-hour ceremony and ribbon cutting, starting at 11 a.m., on Wednesday, June 10.
|6/5/09||JOHNS HOPKINS MEDICINE RETAINS CONSULTING GROUP TO HELP DEVELOP ADVANCED HEALTH CARE SERVICES FOR GOVERNMENT AGENCIES |
Johns Hopkins HealthCare LLC (JHHC), the managed care arm of Johns Hopkins Medicine (JHM), has signed an agreement with The Winkenwerder Company LLC for strategic consulting services, a move designed to build on and expand Johns Hopkins’ longstanding relationships with government health agencies.
|6/4/09||MYSTERY SOLVED: JOHNS HOPKINS SCIENTISTS SAY TINY PROTEIN-ACTIVATOR RESPONSIBLE FOR BRAIN CELL DAMAGE IN HUNTINGTON DISEASE|
Johns Hopkins brain scientists have figured out why a faulty protein accumulates in cells everywhere in the bodies of people with Huntington’s disease (HD), but only kills cells in the part of the brain that controls movement, causing negligible damage to tissues elsewhere. The answer, reported this week in Science, lies in one tiny protein called “Rhes” that’s found only in the part of the brain that controls movement. The findings, according to the Hopkins scientists, explain the unique pattern of brain damage in HD and its symptoms, as well as offer a strategy for new therapy.
|6/1/09||HOPKINS STUDY: WHEN ADULT PATIENTS HAVE ANXIETY DISORDER, THEIR CHILDREN NEED HELP TOO|
In what is believed to be the first U.S. study designed to prevent anxiety disorders in the children of anxious parents, researchers at the Johns Hopkins Children’s Center have found that a family-based program reduced symptoms and the risk of developing an anxiety disorder among these children.
|5/29/09||JOHNS HOPKINS TRANSPLANT TEAM HOLDS SUCCESSFUL?FUNDRAISER|
- ‘Let the Music Move You’ event raises more than $70,000 for transplant research
An evening of opera music featuring Metropolitan opera star Denyise Graves was held recently to raise funds to benefit organ transplant surgery research and care at Johns Hopkins. The event, titled “Let the Music Move You,” was attended by 70 guests at Graves’ home in Bethesda, Md.
|5/29/09||FILM CHRONICLE OF CODY UNSER’S 9-YEAR STRUGGLE WITH PARALYZING TRANSVERSE MYELITIS PREMIERES JUNE 2|
-- Glenn Close narrates documentary featuring her treatment at Johns Hopkins
A documentary history of long-time Johns Hopkins patient Cody Unser, the daughter and granddaughter of Indy 500 car racing greats, will premiere at a benefit June 2 at the Hershey Theater in Hershey, Pa. The event is hosted by Mario Andretti and his wife Dee Ann. Andretti is the only driver to win the Indianapolis 500, the Daytona 500 and the Formula One World Championship.
|5/28/09||THE JOHNS HOPKINS HOSPITAL NAMED TO INTERNATIONAL LIST OF MOST ETHICAL ORGANIZATIONS|
The Ethisphere Institute, a New York-based think-tank established to advance best practices in business ethics and corporate social responsibility, has named The Johns Hopkins Hospital to its 2009 list of the business world’s most ethical companies and institutions.
|5/27/09||TV INDUSTRY FOUNDATION PICKS HOPKINS SCIENTISTS FOR CANCER RESEARCH “DREAM TEAMS”???|
----“Stand Up to Cancer” research funds raised by ABC, CBS, NBC telecast last fall
A TV industry- and celebrity-driven cancer research project has chosen scientists at Johns Hopkins for two of five multi-institutional “dream teams” financed by “Stand Up to Cancer “ grants totaling more than $6 million.
|5/25/09||SURVEY SUGGESTS HIGHER RISK OF FALLS DUE TO DIZZINESS IN MIDDLE-AGED AND OLDER AMERICANS? |
-- Millions unaware of danger from vestibular dysfunction; diabetes a risk factor, along with age
A full third of American adults, 69 million men and women over age 40, are up to 12 times more likely to have a serious fall because they have some form of inner-ear dysfunction that throws them off balance and makes them dizzy, according to Johns Hopkins experts.
|5/20/09||JOHNS HOPKINS PATIENT SAFETY PROGRAM RECEIVES HEALTHCARE INFORMATICS MAGAZINE’S 2009 INNOVATOR AWARD|
Johns Hopkins Medicine’s patient safety program has earned second place in Healthcare Informatics magazine’s eighth annual Innovator Awards.
|5/20/09||HIGH SCHOOL ATHLETES OFFERED FREE SCREENING FOR RISK OF DANGEROUS HEART ABNORMALTIES|
-- “Heart Hype” event staffed by Johns Hopkins heart disease experts to kick-off second annual state campaign
For the second year in a row, volunteer heart disease experts from Johns Hopkins will staff and run Maryland’s only screening program to detect early signs of life-threatening heart abnormalities, including hypertrophic cardiomyopathies, in student athletes.
|5/20/09||SCIENCE WRITERS' SYMPOSIUM|
“Ever Wonder What Gets Your Senses Revving?”
Come spend the day learning about the latest in sensory biology research at the Institute for Basic Biomedical Sciences of the Johns Hopkins University School of Medicine.
|5/19/09||HEART SURGEON DENTON A. COOLEY TO SPEAK AT JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE CONVOCATION|
--Pioneering practitioner and Johns Hopkins graduate chosen by graduates for ceremony on May 22
?Denton A. Cooley, M.D., an American pioneer in heart surgery, will be the guest speaker at the Johns Hopkins University School of Medicine’s 114th convocation on Friday, May 22, 2009 at 10:30 a.m. at the Joseph Meyerhoff Symphony Hall in Baltimore.
|5/18/09||MOCK CPR DRILLS IN KIDS SHOW MANY RESIDENTS FAIL IN KEY SKILLS|
"Staged” CPR drills quickly close the training gaps
Research from the Johns Hopkins Children’s Center exposes alarming gaps in training hospital residents in “first response” emergency treatment of staged cardiorespiratory arrests in children, while at the same time offering a potent recipe for fixing the problem.
NEW LEAD ON MALARIA TREATMENT
OLD DIABETES DRUG TEACHES EXPERTS NEW TRICKS
|5/12/09||RETINAL DISEASE, SIGHT MAY DEPEND ON SECOND SITES|
If two people have the same genetic disease, why would one person go blind in childhood but the other later in life or not at all? For a group of genetic diseases — so-called ciliary diseases that include Bardet-Biedl syndrome, Meckel-Gruber syndrome, and Joubert syndrome — the answer lies in one gene that is already linked to two of these diseases and also seems to increase the risk of progressive blindness in patients with other ciliary diseases.?
|5/10/09||NEW GENES IMPLICATED IN HIGH BLOOD PRESSURE|
Researchers at the Johns Hopkins University School of Medicine, along with an international team of collaborators, have identified common genetic changes associated with blood pressure and hypertension. The study, reporting online next week in Nature Genetics, breaks new ground in understanding blood pressure regulation and may lead to advances in hypertension therapy.
|5/6/09||NEW EVIDENCE TIES GENE TO ALZHEIMER’S|
Of dozens of candidates potentially involved in increasing a person’s risk for the most common type of Alzheimer’s disease that affects more than 5 million Americans over the age of 65, one gene that keeps grabbing Johns Hopkins researchers’ attention makes a protein called neuroglobin.
|5/4/09||JOHNS HOPKINS’ YOUNG ENGINEERS RECEIVE INDUSTRY SUPPORT|
--Johnson & Johnson Fuels Prototype Development of Medical Devices
Metal detectors for removing surgical screws, intensive care walkers and radiological markers for locating tumors—what will they think of next?
NEWS TIPS FROM THE 2009 ANNUAL MEETING OF THE PEDIATRIC ACADEMIC SOCIETIES
|5/1/09||WHEN CELLS REACH OUT AND TOUCH|
J-RNA Production Revs Up During Cell-to-Cell Contact
MicroRNAs are single-stranded snippets that, not long ago, were given short shrift as genetic junk. Now that studies have shown they regulate genes involved in normal functioning as well as diseases such as cancer, everyone wants to know: What regulates microRNAs?
|5/1/09||CHEMICAL FOUND IN MEDICAL DEVICES IMPAIRS HEART FUNCTION|
Researchers at the Johns Hopkins University School of Medicine have found that a chemical commonly used in the production of such medical plastic devices as intravenous (IV) bags and catheters can impair heart function in rats.
|4/30/09||FOLIC ACID MAY HELP TREAT ALLERGIES, ASTHMA |
Folic acid, or vitamin B9, essential for red blood cell health and long known to reduce the risk of spinal birth defects, may also suppress allergic reactions and lessen the severity of allergy and asthma symptoms, according to new research from the Johns Hopkins Children's Center.
|4/28/09||STATEMENT FROM JOHNS HOPKINS ABOUT SWINE FLU SAFETY|
As always, Johns Hopkins' first priority is the safety and care of patients, visitors, employees and students. Experts and officials at Johns Hopkins Medicine are working closely with federal, state and local public health offices during this rapidly changing public health problem. The Johns Hopkins Office of Critical Event Preparedness and Response (CEPAR) has plans for emerging infections. These plans are being implemented as needed, and JHM will take all required steps to help assure your safety.
|4/24/09||SUBURBAN HOSPITAL HEALTHCARE SYSTEM TO JOIN JOHNS HOPKINS MEDICINE|
In a move to build on longstanding ties and to address growing regional interest in more efficient, integrated regional health care services for patients, officials of Suburban Hospital Healthcare System (SHHS)?and The Johns Hopkins Health System Corporation have formally agreed to integrate SHHS into the Johns Hopkins Health System (JHHS).
|4/23/09||JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE RANKED #2 IN NATION|
Once again, the Johns Hopkins University School of Medicine has retained its top-tier ranking in U.S. News & World Report’s edition on the best graduate schools in the nation.
|4/22/09||DOUBLE-LUNG TRANSPLANTS WORK BETTER THAN SINGLE FOR LONG-TERM SURVIVAL|
Having both lungs replaced instead of just one is the single most important feature determining who lives longest after having a lung transplant, more than doubling an organ recipient’s chances of extending their life by over a decade, a study by a team of transplant surgeons at Johns Hopkins shows.
|4/20/09||FORMER NIH DIRECTOR ELIAS ZERHOUNI REJOINS JOHNS HOPKINS MEDICINE AS SENIOR ADVISOR|
It’s a homecoming, of sorts. Elias Zerhouni, M.D., director of the National Institutes of Health (NIH) from 2002 to 2008 and former Johns Hopkins Medicine executive vice dean, returns to Hopkins May 1, 2009, as a senior advisor to Johns Hopkins Medicine.
|4/16/09||EVIDENCE GROWS THAT MATERNAL IMMUNE RESPONSE TO FETAL BRAIN DURING PREGNANCY A KEY FACTOR IN SOME AUTISM|
?-Mouse studies with human antibodies at Hopkins Children’s add weight to earlier research
New studies in pregnant mice using antibodies against fetal brains made by the mothers of autistic children show that immune cells can cross the placenta and trigger neurobehavioral changes similar to autism in the mouse pups\
|4/16/09||AUTOPSY STUDY LINKS PROSTATE CANCER TO SINGLE ROGUE CELL|
One cell…one initial set of genetic changes - that’s all it takes to begin a series of events that lead to metastatic cancer. Now, Johns Hopkins experts have tracked how the cancer process began in 33 men with prostate cancer who died of the disease. Culling information from autopsies, their study points to a set of genetic defects in a single cell that are different for each person’s cancer.
|4/13/09||JOHNS HOPKINS RESEARCHERS AT THE ANNUAL MEETING OF THE AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY |
April 18–22, New Orleans, La.
|4/10/09||IN THE ICU, USE OF BENZODIAZEPINES, OTHER FACTORS MAY PREDICT SEVERITY OF POST-STAY DEPRESSION|
?Psychiatrists and critical care specialists at Johns Hopkins have begun to tease out what there is about a stay in an intensive care unit (ICU) that leads so many patients to report depression after they go home.
JOHNS HOPKINS HONORS YOUNG INVESTIGATORS
PHYSICIAN ALERT: STOP COMMONLY PRESCRIBING STOMACH-UPSET DRUGS FOR ASTHMATICS WITHOUT SERIOUS HEARTBURN
|4/8/09||NEW COMMON PATHWAY IN NEURODEGENERATIVE DISEASE IS A POSSIBLE DOOR TO A POINT OF NO RETURN|
A just-out study suggests that what keeps chronic nervous system diseases such as Alzheimer’s, Huntington’s and ALS going — until they overcome the internal protective mechanisms a body can throw at them — may largely come down to poor conversational skills.
|4/8/09||NEW JHM POLICIES TIGHTEN RULES ON INDUSTRY INTERACTIONS|
-Action seeks elimination of undue industry influence and better oversight of collaborations
Johns Hopkins Medicine has adopted a new policy that significantly limits interactions with industry while ensuring effective, principled and appropriate partnerships with drug and medical device makers.
|4/6/09||COMPENDIUM OF PANCREATIC CANCER BIOMARKERS ESTABLISHED AS STRATEGIC APPROACH TO EARLY-DETECTION RESEARCH|
A cancer scientist from Johns Hopkins has convinced an international group of colleagues to delay their race to find new cancer biomarkers and instead begin a 7,000-hour slog through a compendium of 50,000 scientific articles already published to assemble, decode and analyze the molecules that might herald the furtive presence of pancreatic cancer
GUTSY GERMS SUCCUMB TO BABY BROCCOLI??
|4/2/09||ABC DOCUMENTARY “HOPKINS” WINS PRESTIGIOUS PEABODY AWARD|
-Sequel to original Hopkins 24/7 series focused on young physicians in training
“Hopkins,” the seven-part ABC network news documentary filmed entirely at The Johns Hopkins Hospital and aired in late summer of 2008, is among the 2008 winners of the 68th Annual Peabody Awards for electronic media. Winners, chosen by the Peabody board, were named in a ceremony on April 1 by The University of Georgia's Grady College of Journalism and Mass Communication.
|4/2/09||HOPKINS RANKS AMONG BEST HOSPITALS IN AARP PHYSICIAN SURVEY|
-Johns Hopkins Hospital recommended for Heart, Cancer, “Mystery Diagnoses,” Neurosurgery, and Ophthalmology
A new survey of U.S. physicians commissioned by AARP ranks The Johns Hopkins Hospital among the “most frequently recommended” medical centers for heart disease, cancer, “mystery diagnoses,” neurosurgery and ophthalmology. Results of the survey, conducted by Consumers’ Checkbook, a Washington, D.C.-based nonprofit research organization, are published in AARP magazine’s May/June issue.
|4/1/09||JOHNS HOPKINS’ YOUNG ENGINEERS RECEIVE INDUSTRY SUPPORT|
--Johnson & Johnson Fuels Prototype Development of Medical Devices
Metal detectors for removing surgical screws, intensive care walkers and radiological markers for locating tumors, what will they think of next?
|3/31/09||JOHNS HOPKINS APPOINTS NEW CLINICAL DIRECTOR OF CARDIOLOGY|
– Edward Kasper also to serve as co-director of Heart and Vascular Institute
Physician-science investigator Edward Kasper, M.D., an expert in chronic heart failure and the heart transplantation that often results from the disease, has been named the new clinical director of the Johns Hopkins University School of Medicine’s Division of Cardiology and co-director of the School’s Heart and Vascular Institute.
|3/26/09||THREE JOHNS HOPKINS RESEARCHERS NAMED HOWARD HUGHES MEDICAL INSTITUTE EARLY CAREER SCIENTISTS|
Three researchers at the Johns Hopkins University School of Medicine have been named early career scientists by the Howard Hughes Medical Institute (HHMI). Xinzhong Dong, Ph.D., Joshua Mendell, M.D., Ph.D., and Sinisa Urban, Ph.D., all will remain faculty at Hopkins but also become employees of HHMI, which will provide research funding and salary for the next six years.
|3/24/09||GENETIC CHANGES OUTSIDE NUCLEAR DNA SUSPECTED TO TRIGGER MORE THAN HALF OF ALL CANCERS?|
A buildup of chemical bonds on certain cancer-promoting genes, a process known as hypermethylation, is widely known to render cells cancerous by disrupting biological brakes on runaway growth. Now, Johns Hopkins scientists say the reverse process — demethylation — which wipes off those chemical bonds may also trigger more than half of all cancers.
SAFE DRIVING EDUCATION SHOULD BE PART OF ROUTINE TEEN PHYSICALS, HOPKINS CHILDREN'S EXPERTS SAY
|3/24/09||STARVE A YEAST, SWEETEN ITS LIFESPAN??|
--Johns Hopkins scientists find molecular mechanisms linking sugar production and longevity
Johns Hopkins researchers have discovered a new energy-making biochemical twist in determining the lifespan of yeast cells, one so valuable to longevity that it is likely to also functions in humans.
|3/22/09||HOPKINS SCIENTISTS ID 10 GENES ASSOCIATED WITH A RISK FACTOR FOR SUDDEN CARDIAC DEATH |
One minute, he’s a strapping 40-year-old with an enviable cholesterol level, working out on his treadmill.? The next, he’s dead.
|3/18/09||TRADITIONAL “MATCH DAY” AT JOHNS HOPKINS MARCH |
-School of Medicine fourth-year students gather with classmates and family to learn their residency sites
Although the majority of the nation’s fourth-year medical students can go online to find out which residencies are theirs, the Johns Hopkins University School of Medicine class of ’09 will continue the school’s annual ritual of gathering and opening official letters in the presence of classmates, professors and loved ones.
|3/18/09||6.5 MILLION MORE PATIENTS MIGHT BENEFIT FROM STATINS TO PREVENT HEART ATTACKS, STROKES|
--Study expands on recent findings showing benefits for patients with low cholesterol
Millions more patients could benefit from taking statins, drugs typically used to prevent heart attacks and strokes, than current prescribing guidelines suggest, Johns Hopkins doctors report in a new study.
JOHNS HOPKINS MEDICINE INTERNATIONAL LAUNCHES NEW CARDIAC SURGERY COLLABORATION IN ITALY
|3/11/09||LENGTHY “DAISY CHAIN” TRANSPLANTS POSSIBLE FROM ONE ALTRUISTIC DONOR KIDNEY|
- 10-way swaps of donor kidneys could theoretically give way to dozens or hundreds
A new variation in kidney paired donation (KPD) — pioneered and developed at Johns Hopkins — could theoretically generate an endless number of transplants, researchers report.
|3/11/09||JEREMY NATHANS AWARDED PRESTIGIOUS SCOLNICK PRIZE|
--For Discoveries in Color Vision
March 11, 2009- Jeremy Nathans, M.D., Ph.D., professor of molecular biology and genetics, neuroscience and ophthalmology at the Johns Hopkins University School of Medicine, has been awarded the sixth annual Edward M. Scolnick Prize in Neuroscience by the McGovern Institute at the Massachusetts Institute of Technology. The Scolnick Prize is awarded each year to recognize an individual who has made outstanding advances in the field of neuroscience.
|3/11/09||DIAGNOSTIC ERRORS: THE NEW FOCUS OF PATIENT SAFETY EXPERTS|
--JAMA commentary highlights problem, suggests solutions to reduce the number of diagnoses that are missed, wrong or delayed
Johns Hopkins patient safety experts say it’s high time for diagnostic errors to get the same attention from medical institutions and caregivers as drug-prescribing errors, wrong-site surgeries and hospital-acquired infections. Diagnostic misadventures represent a potentially much larger source of preventable health problems and deaths than many of the more popular targets of safety reform, they say in a commentary in the March 11 issue of the Journal of the American Medical Association.
|3/10/09||SEAWEED AND FIREFLIES BREW MAY GUIDE STEM CELL TREATMENT?FOR PERIPHERAL ARTERY DISEASE|
An unlikely brew of seaweed and glow-in-the-dark biochemical agents may hold the key to the safe use of transplanted stem cells to treat patients with severe peripheral arterial disease (PAD), according to a team of veterinarians, basic scientists and interventional radiologists at Johns Hopkins.
|3/9/09||THE DIFFERENCE BETWEEN EYE CELLS IS…SUMO?|
--Johns Hopkins Researchers Discover Critical Switch in Eye Development
Researchers at the Johns Hopkins University School of Medicine and Washington University School of Medicine have identified a key to eye development — a protein that regulates how the light-sensing nerve cells in the retina form. While still far from the clinic, the latest results, published in the Jan. 29 issue of Neuron, could help scientists better understand how nerve cells develop.
|3/5/09||"PERSONALIZED" GENOME SEQUENCING FINDS DISEASE-CAUSING GENES |
Scientists at the Sol Goldman Pancreatic Cancer Research Center at the Johns Hopkins Kimmel Cancer Center have used "personalized genome" sequencing on an individual with a hereditary form of pancreatic cancer to locate a mutation in a gene called PALB2 that is responsible for initiating the disease. The discovery marks their first use of a genome scanning system to uncover suspect mutations in normal inherited genes.
|3/3/09||JOHNS HOPKINS-AFFILIATED CLEMENCEAU MEDICAL CENTER IN LEBANON|
The Clemenceau Medical Center (CMC) in Beirut, Lebanon, has been awarded the official accreditation of the Joint Commission International (JCI). CMC is one of only two medical centers in Lebanon to hold JCI accreditation.
|2/25/09||JOHNS HOPKINS SAFETY TEAM WORKS TO ELIMINATE BLOODSTREAM INFECTIONS IN THE NATION AND THE WORLD|
- Likely to save the health care industry billions of dollars and tens of thousands of lives annually in the United States alone
A widely heralded Johns Hopkins safety initiative to reduce bloodstream infections in intensive care units (ICUs) was implemented in 30 states starting Feb. 1 and could save an estimated $3 billion dollars and 30,000 lives annually. In addition, the program has been launched in Spain and will begin in the United Kingdom starting in April. Pilot programs are also under discussion with health care leaders in Peru and Chile.
|2/20/09||PROSTATE SPECIFIC ANTIGEN TESTING MAY BE UNNECESSARY FOR SOME OLDER MEN|
Certain men age 75 to 80 are unlikely to benefit from routine prostate specific antigen (PSA) testing, according to a Johns Hopkins study published in the April 2009 issue of The Journal of Urology.
|2/19/09||TWO GENE MUTATIONS LINKED TO MOST COMMON BRAIN CANCERS|
Scientists at the Johns Hopkins Kimmel Cancer Center and Duke University Medical Center have linked mutations in two genes, IDH1 and IDH2, to nearly three-quarters of several of the most common types of brain cancers known as gliomas. Among the findings: people with certain tumors that carry these genetic alterations appear to?survive at least twice as long as those without them.
|2/19/09||CLOT-BUSTER BOOSTS SURVIVAL, DECREASES DISABILITY FOR DEADLY SUBSET OF STROKE|
--Patients continued to improve function six months after treatment
New results from a multicenter study led by Johns Hopkins show that patients who got an experimental clot-busting treatment for a particularly lethal form of stroke were not only dramatically more likely to survive but also continued to shed lingering disabilities six months later.?
|2/17/09||RESEARCHERS EXPLORE NEW DRIVER OF TRANSPLANT REJECTION: PLATELETS|
--“Platelet guy” at Johns Hopkins finds there’s a lot more to these cells than blood clotting
Platelets, tiny and relatively uncharted tenants of the bloodstream known mostly for their role in blood clotting, turn out to also rally sustained immune system inflammatory responses that play a critical role in organ transplant rejection, according to a new report from Johns Hopkins scientists.
|2/16/09||JOHNS HOPKINS LEADS FIRST 12-PATIENT, MULTICENTER “DOMINO DONOR” KIDNEY TRANSPLANT|
Six donor-recipient pairs interchange kidneys in simultaneous, multistate procedure
Surgical teams at The Johns Hopkins Hospital, Barnes-Jewish Hospital in St. Louis and Integris Baptist Medical Center in Oklahoma City successfully completed Saturday the first six-way, multihospital, domino kidney transplant. All six donors — one man and five women, and six organ recipients – four men and two woman — are in good condition, according to Robert Montgomery, M.D., Ph.D., chief transplant surgeon at Johns Hopkins.
|2/15/09||WHAT’S FEEDING CANCER CELLS?|
--Johns Hopkins Researchers Discover How Critical Cancer Gene Controls Nutrient Use
Cancer cells need a lot of nutrients to multiply and survive. While much is understood about how cancer cells use blood sugar to make energy, not much is known about how tey get other nutrients. Now, researchers at the Johns Hopkins University School of Medicine have discovered how the Myc cancer-promoting gene uses microRNAs to control the use of glutamine, a major energy source. The results, which shed light on a new angle of cancer that might help scientists figure out a way to stop the disease, appear Feb. 15 online at Nature.
|2/14/09||THE GENOME'S TRAVELING SALESMEN: TIPS ON NEWSMAKERS AT AAAS|
Transposons — the traveling salesmen of the genome composed of DNA sequences with no fixed address — are the focus of a symposium at the annual meeting of the AAAS led by experts from the Johns Hopkins
|2/9/09||NEW JOHNS HOPKINS IMAGING CENTER TO WIDEN WINDOWS ON THE BRAIN|
It’s a classic academic mismatch: Researchers aren’t able to make use of seminal improvements in technology—often from colleagues just across the street—either because they don’t know about them or because gaining familiarity makes unrealistic demands on their time.
|2/9/09||VOLUNTEER WORK IN GRADE SCHOOLS PRODUCES PERSISTENT HEALTH BENEFIT FOR OLDER BLACK WOMEN|
February 9, 2009- A Johns Hopkins study reveals that older black women who spend time with young children in the classroom are not only more active than similar women who don’t volunteer, but seem to stay active.
|2/9/09||DRUG THERAPY REDUCES HIV TRANSMISSION IN COUPLES REGARDLESS OF CONDOM USE OR SAFE-SEX PRACTICES|
Antiretroviral drug therapy in an HIV-positive man or women can alone help prevent the transmission of HIV to an uninfected partner, regardless of counseling, the patient’s use of condoms or other safe-sex practices, AIDS experts at Johns Hopkins report
|2/8/09||VIRAL-LOAD TESTING: A BETTER WAY TO PREDICT ANTI-HIV, DRUG-TREATMENT FAILURES IN AFRICA|
Johns Hopkins and Ugandan scientists say counting the number of HIV viruses in the blood rather than relying solely on counting the number of circulating HIV-fighting CD4 immune system cells is a far better way to uncover early signs that antiretroviral drugs are losing their punch, and to signal the need to get patients on more potent treatments to keep the disease in check.
|2/4/09||JOHNS HOPKINS OFFERS FREE SOFTWARE TOOL FOR LARGE-SCALE DISASTER "SURGE" PLANNING|
-Computer Modeling Program Developed By Hopkins’ Office of Critical Event Preparedness and Response and Applied Physics Lab Team
A team of Johns Hopkins experts is offering a free, Web-based tool it developed that calculates and predicts in advance the impact on individual hospitals of a flu epidemic, bioterrorist attack, flood or plane crash, accounting for such elements as numbers of victims, germ-carrying wind patterns, available medical resources, bacterial incubation periods and bomb size.
|2/3/09||JOHNS HOPKINS RESEARCHERS DISCOVER NEW SCHIZOPHRENIA GENE|
Researchers at the Johns Hopkins University School of Medicine are one gene closer to understanding schizophrenia and related disorders. Reporting in the Jan. 9 issue of the American Journal of Human Genetics, the team describes how a variation in the neuregulin 3 gene influences delusions associated with schizophrenia.
|2/2/09||HOPKINS TRANSPLANT SURGEONS REMOVE HEALTHY KIDNEY THROUGH DONOR’S VAGINA|
- Minimally invasive organ removal could increase donations, surgeons say
?In what is believed to be a first-ever procedure, surgeons at Johns Hopkins have successfully removed a healthy donor kidney through a small incision in the back of the donor’s vagina.
|2/2/09||JOHNS HOPKINS APPOINTS NEW DIRECTOR OF CARDIOLOGY|
– Gordon Tomaselli also to serve as co-director of Heart and Vascular Institute
Physician-scientist Gordon Tomaselli, M.D., an expert on sudden cardiac death and heart rhythm disturbances, has been named the new director of the Johns Hopkins University School of Medicine’s Division of Cardiology and co-director of the School’s Heart and Vascular Institute.?
|1/30/09||STUDY CONFIRMS PERSISTENCE OF DIVERSITY PROBLEMS IN ACADEMIC MEDICINE|
A survey study believed to be one of the first efforts to put hard numbers around long-held beliefs about diversity in medical school faculties has affirmed that awareness and sensitivity to racial and ethnic diversity are believed by most faculty to be poor and even poorer among faculty who are members of underrepresented minorities.
|1/30/09||TEACHING AN OLD DRUG NEW TRICKS|
--Leprosy medicine holds promise as therapy for autoimmune diseases
A century-old drug that failed in its original intent to treat tuberculosis but has worked well as an antileprosy medicine now holds new promise as a potential therapy for multiple sclerosis and other autoimmune diseases.
|1/29/09||JOHNS HOPKINS MEDICINE INTERNATIONAL APPOINTS NEW CEO AT AL CORNICHE|
-Brings highly experienced team to manage maternity facility
Johns Hopkins Medicine International (JHI), the international arm of Johns Hopkins Medicine, has appointed Ronald S. Lavater chief executive officer of Al Corniche Hospital (Abu Dhabi, UAE), which handles more than 12,000 births and 216,000 outpatient visits a year. Al Corniche Hospital is a Joint Commission International (JCI)-accredited health care facility owned by the Abu Dhabi Health Services Company (SEHA).
|1/27/09||LUNG TRANSPLANTS: DOING MORE IS BETTER AND SAFER, A JOHNS HOPKINS STUDY SUGGESTS|
Transplant surgeons at Johns Hopkins have evidence that hospitals performing at least 20 lung transplant procedures a year, on average, have the best overall patient survival rates and lowest number of deaths from the complex surgery.?
|1/26/09||STATEWIDE STUDY CONFIRMS “PAPERLESS” HOSPITALS ARE BETTER FOR PATIENTS|
Results from a large-scale Johns Hopkins study of more than 40 hospitals and 160,000 patients show that when health information technologies replace paper forms and handwritten notes, both hospitals and patients benefit strongly.
|1/22/09||HOW CHEMOTHERAPY DRUGS BLOCK BLOOD VESSEL GROWTH, SLOW CANCER SPREAD|
--Implications for Further Personalizing Cancer Treatment
Researchers at the Johns Hopkins University School of Medicine have discovered how a whole class of commonly used chemotherapy drugs can block cancer growth. Their findings, reported online this week at the Proceedings of the National Academy of Sciences Early Edition, suggest that a subgroup of cancer patients might particularly benefit from these drugs.
|1/20/09||SURVIVING DANCE CLUB MUSIC (NOISE) WITH HEARING INTACT|
By tweaking a system in the ear that limits how much sound is heard, a global team of researchers has discovered one alteration that shows that the ability of the ear to turn itself down contributes to protecting against permanent hearing loss.
KIDNEY TRANSPLANT SURVIVAL CAN BE LONG-TERM FOR PEOPLE WITH HIV
|1/18/09||LARGE DNA STRETCHES, NOT SINGLE GENES, SHUT OFF AS CELLS MATURE|
--Epigenetic finding adds insight on how cells become brain, liver – and malignant
Experiments at Johns Hopkins have found that the gradual maturing of embryonic cells into cells as varied as brain, liver and immune system cells is apparently due to the shut off of several genes at once rather than in individual smatterings as previous studies have implied.
|1/18/09||GENE SWITCH SITES FOUND MAINLY ON “SHORES,” NOT JUST “ISLANDS” OF THE HUMAN GENOME|
---Study vastly expands prospects for understanding disease and new treatments against colon cancer
Scientists who study how human chemistry can permanently turn off genes have typically focused on small islands of DNA believed to contain most of the chemical alterations involved in those switches. But after an epic tour of so-called DNA methylation sites across the human genome in normal and cancer cells, Johns Hopkins scientists have found that the vast majority of the sites aren’t grouped in those islands at all, but on nearby regions that they’ve named “shores.”
|1/14/09||JOHNS HOPKINS MEDICINE INTERNATIONAL SIGNS MANAGEMENT AGREEMENT WITH PANAMA'S HOSPITAL PUNTA PACIFICA|
Johns Hopkins Medicine International (JHI)—the Baltimore, Maryland, USA-based international arm of Johns Hopkins Medicine—and Hospital Punta Pacífica (HPP) in Panama City, Panama, have entered into a seven-year agreement that gives JHI complete managerial oversight of the 75-bed hospital.
|1/12/09||OLDER WOMEN LESS LIKELY THAN MEN TO BE LISTED FOR KIDNEY TRANSPLANTS|
A Johns Hopkins transplant surgeon has found strong evidence that women over 45 are significantly less likely to be placed on a kidney transplant list than their equivalent male counterparts, even though women who receive a transplant stand an equal chance of survival.
|1/8/09||GROWTH OF NEW BRAIN CELLS REQUIRES ‘EPIGENETIC’ SWITCH|
New cells are born every day in the brain’s hippocampus, but what controls this birth has remained a mystery. Reporting in the January 1 issue of Science, neuroscientists at the Johns Hopkins University School of Medicine have discovered that the birth of new cells, which depends on brain activity, also depends on a protein that is involved in changing epigenetic marks in the cell’s genetic material.
|1/7/09||LOST IN TRANSLATION|
-- Perfectionist protein-maker trashes errors
The enzyme machine that translates a cell’s DNA code into the proteins of life is nothing if not an editorial perfectionist.
|1/6/09||FOUR, THREE, TWO, ONE . . . PTEROSAURS HAVE LIFT OFF!|
--Hopkins researcher reports that ancient flying reptiles used four legs to launch
Pterosaurs have long suffered an identity crisis. Pop culture heedlessly — and wrongly — lumps these extinct flying lizards in with dinosaurs. Even paleontologists assumed that because the creatures flew, they were birdlike in many ways, such as using only two legs to take flight.
NEW HOPE FOR CANCER COMES STRAIGHT FROM THE HEART
VIAGRA’S OTHER TALENTS: TO HELP A ‘SIGNALING’ PROTEIN SHIELD THE HEART FROM HIGH BLOOD PRESSURE DAMAGE
PROLONGED NEVIRAPINE IN BREAST-FED BABIES PREVENTS HIV INFECTION BUT LEADS TO DRUG-RESISTANT HIV