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School of Medicine
Johns Hopkins Medicine
Office of Corporate Communications
Contact: John M. Lazarou
Friday, September 16, 2005
DIGITAL MAMMOGRAPHY BETTER AT FINDING CANCER IN YOUNG WOMEN
A study of 42,760 women at 33 sites across the United States and Canada, including Johns Hopkins, found that digital mammography is better than standard X-ray mammography at locating cancer in young women and those with dense breast. The study, one of the largest breast cancer screening studies ever performed, was conducted by the American College of Radiology, funded by the National Cancer Institute, and reported September 16, 2005 in a special online publication of the New England Journal of Medicine.
Digital mammography detected up to 28% more cancers than X-ray mammography in women 50 and younger, premenopausal and perimenopausal women, and women with dense breasts, according to the American College of Radiology Imaging Network (ACRIN) Digital Mammographic Imaging Screening Trial (DMIST). However, the ACRIN results showed no difference between digital and film (X-ray) mammography in detecting breast cancer for the general population of women.
Nagi Khouri, M.D., director of breast imaging at Johns Hopkins Medicine and the principal investigator for the Hopkins site of the study, says its conclusions have important implications for women. “There is a large percentage of women for whom we can now demonstrate that digital mammography is the preferred modality,” he said.
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