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Infectious Disease Center for Viral Hepatitis

Research

The Center has extensive programs in basic research related to hepatitis B virus (HBV) and hepatitis C virus (HCV) infections, including:

Field

Leader

Research Focus

  • Clinical Research

Sulkowski

  • Clinical trials of interferon-based and small-molecule therapy for HCV infection
  • Epidemiology
  • Pathogenesis

Thomas

  • Determinants of the progression of liver disease during chronic HCV infection
  • Pathogenesis of HIV-HCV coinfection
  • Human Genetics
  • HIV/HBV Coinfection

Thio

  • Human genetic variation affecting the outcomes of HBV and HCV infections
  • Treatment and virology of HBV and HIV coinfection
  • Immunology (Cellular)

Cox

  • Cellular immune responses to HCV during acute and chronic infection
  • Mechanisms of cellular immune failure during the transition from acute to chronic infection
  • Immunology (Innate)
  • Hepatic Inflammation

Balagopal

  • Microbial translocation and Kupffer cells in HIV-HCV coinfection
  • In situ liver studies of HIV-HCV pathogenesis
  • Virology / Evolution
  • Immunology (humoral)

Ray

  • Evolution and immune evasion of the HCV genome during acute and chronic infection
  • Determinants of neutralization of HCV by antibodies

 

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