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The Johns Hopkins Infectious Disease Center for Viral Hepatitis

Research

The Center has extensive programs in basic research related to hepatitis B virus (HBV) and hepatitis C virus (HCV) infections, including:

Field / LeaderResearch Focus

Clinical Research
  Sulkowski

  • Clinical trials of interferon-based and small-molecule therapy for HCV infection

Epidemiology
  Thomas

  • Determinants of the progression of liver disease during chronic HCV infection
Human Genetics
  Thio
  • Human genetic variation affecting the outcomes of HBV and HCV infections
Immunology (Cellular)
  Cox
  • Cellular immune responses to HCV during acute and chronic infection
  • Mechanisms of cellular immune failure during the transition from acute to chronic infection
Immunology (Humoral)
  Netski
  • Humoral immune response to HCV during acute and chronic HCV infection
  • Determinants of neutralization of HCV by antibodies
Virology / Evolution
  Ray
  • Evolution of the HCV genome during acute and chronic infection
  • Virologic mechanisms of immune evasion by HCV
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