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Molecular Imaging of Infectious Diseases: Current Status and Future Challenges

This daylong symposium showcast the latest developments in the field of Infectious Disease Imaging and featured a dozen or so speakers with cross disciplinary expertise from all around the country. It was held on Friday, September 21, 2012 at the Natcher Conference Center in Bethesda, MD. A poster session was held during lunch.

Agenda

08:00-08:30a Light Breakfast

Introduction
08:30-08:55a   Challenges in Infectious Disease: Need for Imaging
                           Sanjay K. Jain, MD, Johns Hopkins University
09:00-09:25a   Overview of Molecular Imaging  
                           Dima A. Hammoud, MD, NIH   
09:30-09:55a   Molecular Imaging Tools for Cardiovascular Infection and Inflammation
                           Farouc A. Jaffer, MD, PhD, Massachusetts General Hospital

10:00-10:20a Coffee Break

Molecular Imaging of the Immune System: Targeting the Host
10:20-10:45a  Cytokine and Chemokine Receptor Imaging 
                          Gary D. Luker, MD, University of Michigan
10:50-11:15a  Translocator Protein (TSPO) as an Inflammatory Marker
                          H. Charles Manning, PhD, Vanderbilt University
11:20-11:45a  PET imaging of T-lymphocytes Using Reporter Genes
                          Caius Radu, MD, University of California, Los Angeles
11:50-12:15a  Labeling of Immune Cells Using Iron Oxide Particles
                          Erik M. Shapiro, PhD, Michigan State University

12:20-01:20p Lunch and Poster Session

Molecular Imaging of Infection: Targeting the Pathogen I
01:20-01:45p  Optical Imaging Applications for Mycobacterial Lung Infections
                          Jeffrey D. Cirillo, PhD, Texas A&M
01:50-02:15p  Imaging Viral Vector Distribution in Small Animals  
                          Michael A. Barry, PhD, Mayo Clinic
02:20-02:45p  Maltodextrin-based Probes to Detect Bacteria
                          Niren Murthy, PhD, University of California, Berkeley

02:50-03:10p Coffee Break

Molecular Imaging of Infection: Targeting the Pathogen II
03:10-03:35p  PET Based Bacteria-Specific Tracers  
                          Edward A. Weinstein, MD, PhD, Johns Hopkins University
03:40-04:05p  Anti-infectious Drug Chemotherapeutics in Animal Models  
                          Peter J. Tonge, PhD, Stony Brook University
04:10-04:35p  Use of PET and SPECT for Detecting Bacteria in Humans 
                          Steve Cho, MD, Johns Hopkins University

04:40-05:00p Wrap up

Guidelines for posters

The poster boards will be 4 feet tall by 6 feet wide and mounted on stands. Your poster should fit on these boards and cover most of the surface. Thumbtacks will be available onsite for mounting the posters.

A scientific committee reviewed all the abstracts and the top 3 submissions from students were each awarded a $500 honorarium (funded through Ci3R-JHU). Government employees were not eligible for this award. In addition, one abstract judged to be amongst the top few was also selected for a platform presentation (in addition to the poster presentation) and will be presented just before the start of the afternoon session.

1.       Winston Liu, University of Maryland, College Park, MD: A Novel Semi-automatic Algorithm for Spinal Cord Volume and Area Analysis in HAM/TSP and MS

2.       Neil Mendhiratta, New York University School of Medicine, New York, NY: Accurate and Robust Quantification of Hybrid MRI-PET and PET-CT Images through a Novel Joint-Segmentation Method

3.       Supriya Pokkali & Ciaran Skerry (shared), Johns Hopkins University School of Medicine, Baltimore, MD: Assessment of M. tuberculosis PknD as a recombinant CNS TB vaccine

Platform presentation:

Guanshu Liu, Johns Hopkins University School of Medicine, Baltimore, MD: MRI detection of bacteria through endogenous CEST contrast 

Please contact Sanjay K. Jain, MD (410-502-8241; sjain5@jhmi.edu) or Dima A. Hammoud, MD (301-402-3041; hammoudd@cc.nih.gov) for more information.

 

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