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Equipment

The following equipment for is available for small animal imaging (mice, rats, guinea pigs, rabbits and other similar sized animals) :

NanoSPECT/CT in vivo Animal Imager

NanoSPECT/CT Small Animal Imager

Dual-Detector System with integrated X-Ray CT Module system including 2 broadband NaI(Tl) SPECT detectors with transaxial field-of-view (FOV) of up to 20 cm and axial field-of-view of up to 27 cm due to helical scan data acquisition. User interchangeable multi-pinhole aperture plates and parallel hole collimators allow multiplexed, multi-pinhole high resolution (<0.5 mm), high sensitivity (>250-400 cps/MBq) SPECT imaging. Collimators and aperture plate sets for high-sensitivity or high-resolution imaging are also available. Detector hardware and software includes multi-channel analysis of SPECT emissions with energies ranging from 25 keV to 250 keV (I-125 to In-111) and simultaneous acquisition of dual-isotope images in separate energy windows with multi-channel analysis for spectral unfolding. Integrated cone-beam X-ray CT system on same axis as SPECT system with fixed axial offset (center-to-center plane) allows seamless combined X-ray CT and SPECT imaging. Adjustable 65 kVp, 0.18 mA X-ray source with < 5 micron spot size, available energy settings provide high-resolution CT (40 µm voxel).

Users fee is $175 per hour for each scheduled hour for the SPECT or the CT component*. These fees are refundable up to 48 hours prior to the scheduled time if it needs to be cancelled. User fee includes anesthesia supplies, use of the animal bed and environmental controls, remote data retrieval and use of advanced image analysis on our workstations. However, it does not include the cost of any radiotracers or other material (if required) for imaging.

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Philips Mosaic HP Small Animal PET Imager

Philips Mosaic HP Small Animal PET Imager

Advanced Positron Emission Tomography (PET) system dedicated for preclinical imaging research that offers unmatched flexibility for imaging small and medium size animals (mice to monkey heads) due to an 18 cms bore size. The system offers comprehensive research capabilities including quantitative measurement of the biodistribution of positron-emitting isotopes, tumor growth monitoring through longitudinal studies, evaluation of new biomarkers for diagosis and therapy of various diseases in oncology, cardiology and neurology. The system includes: gantry that houses the detector assembly (LYSO crystals, light guide, and photomultiplier tubes), the transmission source, holder, the manual insertion mechanism, and collimator, as well as an integrated laser positioning system.

Users fee is $175 per hour for each scheduled hour for the PET component*. These fees are refundable up to 48 hours prior to the scheduled time if it needs to be cancelled. User fee includes anesthesia supplies, use of the animal bed and environmental controls, remote data retrieval and use of advanced image analysis on our workstations. However, it does not include the cost of any radiotracers or other material (if required) for imaging.

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CeraTom CT

CereTom 8-slice CT Imager

CereTom 8-slice clinical CT scanner with a large bore of 32.5 cm (318 mm), delivers the highest quality CT images and contrast perfusion scans. Due to its powerful X-ray source and rapid scan times, it can also perform angiography. The small animal scanning platform allows for imaging guinea pigs, rabbits and other small animals. The Barco’s Voxar 3D™ advanced visualization software package allows for 2D, 3D and MPR viewing. 1.25, 2.5, 5.0 and 10.0 mm slice thickness with CT data acquisition in multiple protocols is available. This imager complements the CT component of the NanoSPECT/CT but is primarily used for imaging large animals.

Users fee is $175 per hour for each scheduled hour*. These fees are refundable up to 48 hours prior to the scheduled time if it needs to be cancelled. User fee includes anesthesia supplies, use of the animal bed and environmental controls, remote data retrieval and use of advanced image analysis on our workstations. However, it does not include the cost of any contrast agents or other material (if required) for imaging.

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Vevo 770 Small Animal Ultrasound System

The Vevo 770 system enables the visualization and quantification of small animal anatomical targets, hemodynamics and therapeutic interventions with resolution as low as 30 microns (high frequency scanhead) and frame rates up to 240 fps.Vevo 770

  • B-mode (2D) imaging for anatomical visualization and quantification.
  • M-mode for visualization and quantification of wall motion in cardiovascular research, single line acquisition allows for the very high-temporal (1000 fps) resolution necessary for analysis of LV function.
  • Anatomical M-Mode for adjustable anatomical orientation in reconstructed M-Mode imaging.
  • Pulsed-Wave Doppler (PW) for quantification of blood flow.
  • 3D Imaging for anatomical and vascular visualization, when combined with either B-mode, Power Doppler, or Contrast Imaging; allows for quantification of volume and vascularity within a defined anatomical structure.

Users feeis $135 per hour for each scheduled hour*. These fees are refundable up to 48 hours prior to the scheduled time if it needs to be cancelled. User fee includes anesthesia supplies, use of the animal bed and environmental controls, remote data retrieval and use of advanced image analysis on our workstations. However, it does not include the cost of any contrast agents or other material (if required) for imaging.

Schedule study

Ancillary equipment and services

Animal bed
  • The animal bed and environmental controls are designed to provide monitoring and maintenance of ambient temperatures during imaging. They can also be used for containment of pathogen free animals.
  • Respiratory and cardiac gating to eliminate artifacts due to respiration or cardiac activity may be available on request.
  • A  high-speed workstation with ultra high speed graphics card and advanced image analysis software is available for reconstruction, data retrieval and advanced image analysis.
  • All imaging data will be available in DICOM and Amira formats. However, due to limited storage space, we highly encourage all users to copy their imaging data elsewhere. We do not provide guarantees for the integrity of these data for extended periods, after the completion of imaging.

Please contact us with any questions or concerns at 410-614-9501.

 

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Whether crossing the country or the globe, we make it easy to access world-class care at Johns Hopkins.

U.S. 1-410-464-6713 (toll free)
International +1-410-614-6424

 

 
 
 
 
 

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