Alan F. Scott, PhD
Associate Professor, Institute of Genetic Medicine
Director, The Genetic Resources Core Facility
The Johns Hopkins University
Center for Medical Genetics
600 N Wolfe St
Baltimore, MD 21287-4925, USA
Phone: (410) 955-2553
Fax: (410) 614-9752
URL: http://grcf.med.jhu.edu, www.CIDR.jhmi.edu, rsng.nhlbi.nih.gov
My research is focused on development of high throughput methods for SNP genotyping through the Genetic Resources Core Facility. We have evaluated various approaches to this problem and are currently centering on bead arrays developed by Illumina, Inc. We are developing bead array assays that will identify common SNPs in up to 200 candidate genes for non-syndromic cleft lip and palate and isolated craniosynostosis. We expect that these arrays will identify the common haplotypes in human populations and allow us to test for haplotype associations with disease.
Other interests include the annotation of functional information for genes in OMIM/LocusLink by reviewing the biomedical literature. The goal of this effort is to attach biological information to the human genome sequence as an aid for disease gene identification.
Activities: Preceptor in the Predoctoral Training Program in Human Genetics and Molecular Biology.