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This year will be the year with the highest number of TB cases and TB deaths in recorded history. Despite such sobering statistics, there is a paucity of new tools with which to combat tuberculosis:
1891 - last effective diagnostic for latent tuberculosis
1921 - last vaccine for tuberculosis
1967 - last new first line drug class for treatment of tuberculosis until
2012 - Approval of Bedaquiline for multi-drug resistant tuberculosis
Moreover, the expanding HIV/AIDS epidemic is also fueling the spread of TB as well as drug-resistant forms of TB
The mission of The Center for Tuberculosis Research Laboratory is to apply medical technology towards basic advances in our understanding of the pathogenesis of TB, host immunity to TB, mechanisms of spread, and animal models which better emulate the pathology of human disease. With these basic tools we intend to build a translational bridge to more effective drugs, vaccines, and diagnostics for tuberculosis.
115th General Meeting of the American Society for Microbiology, May 30-June 2, 2015, New Orleans LA
American Thoracic Society, May 15-20, 2015, Denver, CO
55th Interscience Conference on on Antimicrobial Agents and Chemotherapy, September 18-21, 2015, San Diego, CA